Down syndrome with microgranular variant of acute promyelocytic leukemia in a child: a case report
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چکیده
منابع مشابه
Down syndrome with microgranular variant of acute promyelocytic leukemia in a child: a case report
BACKGROUND Acute promyelocytic leukemia (APL) accounts for less than 10% of pediatric AML. Cases of APL in Down syndrome (DS) have been described in the literature rarely and it is rarer still to find the microgranular variant (M3v) of APL in trisomy 21 patients. CASE PRESENTATION We present a case of a five-year-old female with Down syndrome diagnosed with acute promyelocytic leukemia (APL)....
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Acute promyelocytic leukemia (APL) should be distinguished from other subtypes of acute myeloid leukemia (AML) because of the increased risk of disseminated intravascular coagulation (DIC) and its response to arsenic compounds and retinoids. Some cases of AML seem morphologically similar to the microgranular variant of APL (French-AmericanBritish [FAB] AML-M3v) but lack the t(15;17). We evaluat...
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ژورنال
عنوان ژورنال: Journal of Medical Case Reports
سال: 2007
ISSN: 1752-1947
DOI: 10.1186/1752-1947-1-147